Alzheimer’s disease is a neurological disorder that progressively affects the brain cells. It is sometimes accompanied with dementia and commonly seen in elderly people. It ultimately leads to impaired cognitive functions and loss of memory. Widely used drugs such as donepezil and galantamine successfully abate mild to moderate symptoms of the disease though they have profound side effects. Natural products have been a source of medicine for over thousands of years. Plant secondary metabolites such as alkaloids, flavonoids, terpenoids, etc. are major sources of such medicines. In recent times, the use of natural products to treat various diseases has gained a lot of popularity. Extensive research is being undertaken to identify and isolate various natural products that can be used to not only reduce the disease symptoms but also as a permanent cure. The review article aims to summarize the effects of various natural products and their neuroprotective mechanisms that can be helpful to cure Alzheimer’s disease.
Acetylcholine esterase (AChE) Alzheimer’s disease (AD) plant secondary metabolites Aβ aggregation
Research Society for the Study of Diabetes in India
RSSDI/HQ/Grants/2017/342
RSSDI/HQ/Grants/2017/342
Primary Language | English |
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Subjects | Health Care Administration |
Journal Section | Clinical Research |
Authors | |
Project Number | RSSDI/HQ/Grants/2017/342 |
Publication Date | October 9, 2021 |
Submission Date | March 9, 2021 |
Acceptance Date | March 30, 2021 |
Published in Issue | Year 2021 Volume: 38 Issue: 4 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.