Research Article
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COVİD-19 HASTALARINDA İŞİTME KAYBI

Year 2022, Volume: 29 Issue: 3, 306 - 312, 30.09.2022
https://doi.org/10.17343/sdutfd.1070586

Abstract

Amaç
Dünya çapında bilim insanları, COVID-19'dan iyileşen
hastaları takip etmeye devam ediyorlar. Bu hastalarda
gözlemlenen uzun süreli kalıcı semptomları ve kalıcı
hasarları yayınlıyorlar. Bu çalışma, saf ses odyometrisi
kullanılarak ölçülen saf ses ortalamaları temelinde
COVID-19 hastalarında işitme kaybını değerlendirmeyi
amaçladı.
Gereç ve Yöntem
Bu geriye dönük veri analizi çalışmasında, COVID-
19'lu hastaneye yatırılmamış hastaların saf ses
ortalamaları, COVID-19'a yakalanmadan 1 yıl önce
ve sonra karşılaştırıldı. Sürekli değişkenler ortalama
± standart sapma (SD) olarak, kategorik değişkenler
ise sayı (n) ve yüzde (%) olarak sunuldu. Tüm veriler
normal dağılım gösterdi. Bu nedenle, ölçümler arasındaki
anlamlı farklılıkları belirlemek için bir parametrik
test türü olan eşleştirilmiş t testi kullanılmıştır.
Bulgular
Sol ve sağ kulakların kemik ve hava yollarında ölçülen
saf ses ortalamalarına göre, COVID-19 sonrası
hastaların saf ses eşik değerlerinde anlamlı bir artış
bulundu (tümü için p<0,001). COVID-19 öncesi ve
sonrası sol kulak hava yolunun saf ton ortalamaları
yaşlı erişkinlerde (41-64 yaş) genç yetişkinlere (18-40
yaş) göre daha yüksekti (p=0.040).
Sonuç
COVID-19 her iki kulağın kemik ve hava yollarını etkileyerek
farklı frekanslarda farklı düzeylerde işitme
kaybına neden olmaktadır. COVID-19'un komplikasyonları
üzerine yapılan araştırmalar, işitme kaybı testlerini
içermeli ve olası işitme kaybını önlemek için çalışmalar
yapılmalıdır.

Supporting Institution

yok

Project Number

yok

Thanks

yok

References

  • 1. Li K, Wu J, Wu F, et al. The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Invest Radiol.2020;55(6):327-31. doi:10.1097/RLI.0672
  • 2. Ahmad I, Rathore FA. Neurological manifestations and comp- lications of COVID-19: A Literature Review. J ClinNeurosci. 2020;13(5):667-73.doi: 10.1016/j.jiph.2020.03.019
  • 3. Leonardi M, Padovani A, McArthur JC. Neurological manifestations associated with COVID19: a review and a call for action. J Neurol. 2020;267(6):1573-6.
  • 4. Li B, Yang J, Zhao F, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. ClinRes- Cardiol. 2020;109(5):531‐8. doi:10.1007/s00392-020-01626-9
  • 5. Hunt RH, East JE, Lanas A, et al. COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist. Dig- Dis2021;39:119-39. doi: 10.1159/000512152
  • 6. TR. Ministry of Health Covid-19 patients follow-up guide, 2021. Accessed from::https://toraks.org.tr/site/sf/nmf/pre_migration/ 0cd6655ae86e94eec61e88ab75cc757d8eaa1df39ce- 43d3c871b3d715afde5b6.pdf. Accessed time: 05.06.2021
  • 7. Chen X, Fu YY, Zhang TY. Role of Viral infection in sudden hearing loss. J IntMedRes. 2019;47(7):2865–72. doi: 10.1177/0300060519847860.
  • 8. TR. Ministry of Family, Laborand Social Security. Health and surve illance guide in working life, 2018. Accessed from: https:// www.ailevecalisma.gov.tr/medias/4591/rehber03.pdf. Accessed time: 05.06.2021
  • 9. Mustafa MW. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41(3) doi: 10.1016/j.amjoto.2020.102483.
  • 10. Karimi-Galougahi M, Naeini AS, Raad N, et al. Vertigo and hearing loss during the COVID-19 pandemic - is there an association? ActaOtorhinolaryngolItal. 2020;40:463-5. doi: 10.14639/0392-100X-N0820
  • 11. Koumpa FS, Forde CT, Manjaly JG. Sudden irreversible hearing loss post COVID-19. BMJ Case Reports CP 2020;13,13(11):e238419 doi:10.1136/bcr-2020-238419.
  • 12. Sriwijitalai W, Wiwanitkit V. Hearing loss and COVID-19: A note. AmericanJournal of Otolaryngology -Head and Neck Medicine and Surgery;2020;41(3). doi:10.1016/j.amjoto.2020.102473
  • 13. Han W, Quan B, Guo Y, et al. The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019. Journal of Medical Virology.2020;92(5):461-3. doi:10.1002/ jmv.25711
  • 14. Kim J, Jung J, Moon IS, Lee HK, Lee WS. Statistical analysis of puretone audiometry and caloric test in herpes zosteroticus. ClinExpOtorhinolaryngol. 2008;1(1):15-9.
  • 15. Kim CH, Choi H, Shin JE. Characteristics of hearing loss in patients with herpes zosteroticus. Medicine (Baltimore). 2016;95(46):e5438.
  • 16. Acharya A, Kevadiya BD, Gendelman HE, Byrareddy SN. SARSCoV- 2 Infection Leads to Neurological Dysfunction. J NeuroimmunePharmacol2020; 15:167–73.
  • 17. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, vanGoor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631-7. doi: 10.1002/ path.1570.
  • 18. Iroegbu JD, Ifenatuoha CW. Ijomone OM. Potential neurological impact of coronaviruses: implications for the novel SARSCoV- 2. NeurolSci. 2020;41(6):1329-37.
  • 19. Kalcioglu MT, Cag Y, Kilic O, Tuysuz O. COVID-19 cause sudden sensorineural hearing loss? Int J Infect Dis.2020;101:205 doi:10.1016/j.ijid.2020.09.1468.
  • 20. Maharaj S, BelloAlvarez M, Mungul S, Hari K. Otologic dysfunction in patients with COVID-19: a systematic review. LaryngoscopeInvestigOtolaryngol.2020;5(6):1192–6. doi: 10.1002/ lio2.498.
  • 21. Saniasiaya J. Hearing loss in SARS-CoV-2: What do we know? EarNoseThroat J. 2020;100(2):152-4. doi: 10.1177/0145561320946902.
  • 22. Taneja MK. Deafness in COVID-19. Indian J Otol. 2020;26(2):68- 70 doi:10.4103/indianjotol.INDIANJOTOL_83_20
  • 23. Yaseen N K, Al-Ani R M, Ali Rashid R. COVID-19-related sudden sensorineural hearing loss. Qatar medical journal, 2021(3), 58. https://doi.org/10.5339/qmj.2021.58
  • 24. Edwards M, Muzaffar J, Naik P, Coulson C. Catastrophic bilateral sudden sensorineural hearing loss following COVID-19. BMJ Case Rep. 2021 ;14(6):e243157. doi: 10.1136/bcr-2021- 243157.
  • 25. 25. Koumpa F S, Forde C T, Manjaly J G. Sudden irreversible hearing loss post COVID-19. BMJ case reports 2020;13(11); e238419. https://doi.org/10.1136/bcr-2020-238419

HEARING LOSS IN PATIENTS WITH COVID-19

Year 2022, Volume: 29 Issue: 3, 306 - 312, 30.09.2022
https://doi.org/10.17343/sdutfd.1070586

Abstract

Objective
Worldwide, scientists continue to follow-up on patients
recovered from COVID-19 and have published the
long-term persistent symptoms and permanent
damage observed in various tissues. The present
study aimed to evaluate hearing loss in patients
with COVID-19 on the basis of pure tone averages
measured using pure tone audiometry.
Material and Method
In this retrospective data analysis study, pure
tone averages of non-hospitalised patients with
COVID-19 were compared over 1 year before and
after contracting COVID-19. Continuous variables
were presented as mean ± Standard deviation
(SD) and categorical variables were presented as
number (n) and percentage (%). All data showed
normal distribution. Therefore, paired t-test, a type of
parametric test, was used to identify the significant
differences between the measurements.
Results
The pure tone threshold values of patients increased
significantly after COVID-19 (p0.001 for all) based on
puretone averages measured in the bones and airways
of theleftandrightears. Olderadults (41–64 yearsold)
had a greater difference in puretone averages of the
left ear airway before and after COVID-19 (p=0.040)
than younger adults (18–40 yearsold).
Conclusion
COVID-19 affects both ears' bones and airways,
causing varying degrees of hearing loss at different
frequencies. Hearing loss tests should be included
in COVID-19 complications research, and clinicians
should be given advice on how to avoid hearing loss.

Project Number

yok

References

  • 1. Li K, Wu J, Wu F, et al. The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Invest Radiol.2020;55(6):327-31. doi:10.1097/RLI.0672
  • 2. Ahmad I, Rathore FA. Neurological manifestations and comp- lications of COVID-19: A Literature Review. J ClinNeurosci. 2020;13(5):667-73.doi: 10.1016/j.jiph.2020.03.019
  • 3. Leonardi M, Padovani A, McArthur JC. Neurological manifestations associated with COVID19: a review and a call for action. J Neurol. 2020;267(6):1573-6.
  • 4. Li B, Yang J, Zhao F, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. ClinRes- Cardiol. 2020;109(5):531‐8. doi:10.1007/s00392-020-01626-9
  • 5. Hunt RH, East JE, Lanas A, et al. COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist. Dig- Dis2021;39:119-39. doi: 10.1159/000512152
  • 6. TR. Ministry of Health Covid-19 patients follow-up guide, 2021. Accessed from::https://toraks.org.tr/site/sf/nmf/pre_migration/ 0cd6655ae86e94eec61e88ab75cc757d8eaa1df39ce- 43d3c871b3d715afde5b6.pdf. Accessed time: 05.06.2021
  • 7. Chen X, Fu YY, Zhang TY. Role of Viral infection in sudden hearing loss. J IntMedRes. 2019;47(7):2865–72. doi: 10.1177/0300060519847860.
  • 8. TR. Ministry of Family, Laborand Social Security. Health and surve illance guide in working life, 2018. Accessed from: https:// www.ailevecalisma.gov.tr/medias/4591/rehber03.pdf. Accessed time: 05.06.2021
  • 9. Mustafa MW. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41(3) doi: 10.1016/j.amjoto.2020.102483.
  • 10. Karimi-Galougahi M, Naeini AS, Raad N, et al. Vertigo and hearing loss during the COVID-19 pandemic - is there an association? ActaOtorhinolaryngolItal. 2020;40:463-5. doi: 10.14639/0392-100X-N0820
  • 11. Koumpa FS, Forde CT, Manjaly JG. Sudden irreversible hearing loss post COVID-19. BMJ Case Reports CP 2020;13,13(11):e238419 doi:10.1136/bcr-2020-238419.
  • 12. Sriwijitalai W, Wiwanitkit V. Hearing loss and COVID-19: A note. AmericanJournal of Otolaryngology -Head and Neck Medicine and Surgery;2020;41(3). doi:10.1016/j.amjoto.2020.102473
  • 13. Han W, Quan B, Guo Y, et al. The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019. Journal of Medical Virology.2020;92(5):461-3. doi:10.1002/ jmv.25711
  • 14. Kim J, Jung J, Moon IS, Lee HK, Lee WS. Statistical analysis of puretone audiometry and caloric test in herpes zosteroticus. ClinExpOtorhinolaryngol. 2008;1(1):15-9.
  • 15. Kim CH, Choi H, Shin JE. Characteristics of hearing loss in patients with herpes zosteroticus. Medicine (Baltimore). 2016;95(46):e5438.
  • 16. Acharya A, Kevadiya BD, Gendelman HE, Byrareddy SN. SARSCoV- 2 Infection Leads to Neurological Dysfunction. J NeuroimmunePharmacol2020; 15:167–73.
  • 17. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, vanGoor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631-7. doi: 10.1002/ path.1570.
  • 18. Iroegbu JD, Ifenatuoha CW. Ijomone OM. Potential neurological impact of coronaviruses: implications for the novel SARSCoV- 2. NeurolSci. 2020;41(6):1329-37.
  • 19. Kalcioglu MT, Cag Y, Kilic O, Tuysuz O. COVID-19 cause sudden sensorineural hearing loss? Int J Infect Dis.2020;101:205 doi:10.1016/j.ijid.2020.09.1468.
  • 20. Maharaj S, BelloAlvarez M, Mungul S, Hari K. Otologic dysfunction in patients with COVID-19: a systematic review. LaryngoscopeInvestigOtolaryngol.2020;5(6):1192–6. doi: 10.1002/ lio2.498.
  • 21. Saniasiaya J. Hearing loss in SARS-CoV-2: What do we know? EarNoseThroat J. 2020;100(2):152-4. doi: 10.1177/0145561320946902.
  • 22. Taneja MK. Deafness in COVID-19. Indian J Otol. 2020;26(2):68- 70 doi:10.4103/indianjotol.INDIANJOTOL_83_20
  • 23. Yaseen N K, Al-Ani R M, Ali Rashid R. COVID-19-related sudden sensorineural hearing loss. Qatar medical journal, 2021(3), 58. https://doi.org/10.5339/qmj.2021.58
  • 24. Edwards M, Muzaffar J, Naik P, Coulson C. Catastrophic bilateral sudden sensorineural hearing loss following COVID-19. BMJ Case Rep. 2021 ;14(6):e243157. doi: 10.1136/bcr-2021- 243157.
  • 25. 25. Koumpa F S, Forde C T, Manjaly J G. Sudden irreversible hearing loss post COVID-19. BMJ case reports 2020;13(11); e238419. https://doi.org/10.1136/bcr-2020-238419
There are 25 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Gökmen Özceylan 0000-0002-2388-4158

Dilek Toprak 0000-0001-5119-9089

Project Number yok
Publication Date September 30, 2022
Submission Date February 13, 2022
Acceptance Date April 7, 2022
Published in Issue Year 2022 Volume: 29 Issue: 3

Cite

Vancouver Özceylan G, Toprak D. HEARING LOSS IN PATIENTS WITH COVID-19. Med J SDU. 2022;29(3):306-12.

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